Label-Free In-Line Characterization of Immune Cell Culture using Quantitative Phase Imaging

Abstract excerpt

Cell therapies, including T cell immunotherapies, offer promising treatments for previously untreatable diseases, but their widespread use is hindered by challenges in monitoring therapeutic cells during culture -- impacting consistency, potency, and cost. This work demonstrates the use of quantitative phase imaging (QPI), specifically a compact, non-interferometric form called quantitative oblique back illuminati...

Topics

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• Cell Cycle
• Cell Lineage
• Cell Movement
• Cell Tracking
• Cytological Techniques
• Microscopy, Phase-Contrast
• Phenotype
• Single-Cell Analysis

Identifiers and source

Literature Corpus work

8c3f5648-82c1-5d3f-82ec-dfb4c0924ac8

DOI

10.1101/2025.04.22.649403