Article

Dopamine depletion in Parkinson’s increases directed but not random exploration

2025-11-11

Abstract excerpt

<p>We investigated how patients with Parkinson’s disease (PD) manage the explore–exploit trade-off in a structured reward-learning task. Patients were tested either on (N=34) or off (N=34) dopaminergic medication (levodopa), with age-matched polyneuropathy patients serving as controls (N=35). Behaviorally, patients off medication showed marked learning and decision-making deficits, characterized by overexploration...

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Literature Corpus work: 8c3dcf18-0019-5fb3-8358-c27d6681a588
DOI: 10.31234/osf.io/y2buv_v1

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