Article

Atherosclerotic plaque iron accumulation characterizes a distinct phase of intra-plaque haemorrhage and is associated with inflammation and remodelling

2026-04-30

Abstract excerpt

Intraplaque haemorrhage (IPH) is a hallmark of advanced atherosclerosis and a major risk factor for ischemic stroke and myocardial infarction. Current IPH classification focusses on extravascular erythrocyte presence as a proxy of acute bleeding, where iron detection generally indicates older haemorrhages. While often used interchangeably, a comprehensive analysis of transcriptional and metabolic context and impac...

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Literature Corpus work: 8be1654b-4d27-5cfc-887e-c57942e23197
DOI: 10.64898/2026.04.27.721220

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