Article

LRH-1 as a key regulator of estrogen responses in breast cancer cells

2010-01-01

Abstract excerpt

Liver receptor homolog-1 (LRH-1; NR5A2) is an orphan member of the Ftz-F1 family of nuclear receptors, which comprises four members (NR5A1-NR5A4). LRH- 1 has been linked to a number of key developmental, metabolic and proliferative processes and is known to play an important role in the regulation of cholesterol biosynthesis, lipid homeostasis and the control of steroid aromatisation. In this respect, LRH-1 is rec...

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Literature Corpus work: 8b9e4070-2021-5354-b3d0-25369111695e
DOI: 10.25560/10685

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