Article

ModuleDiscoverer: Identification of regulatory modules in protein-protein interaction networks

2017-03-23

Abstract excerpt

The identification of disease associated modules based on protein-protein interaction networks (PPINs) and gene expression data has provided new insights into the mechanistic nature of diverse diseases. A major problem hampering their identification is the detection of protein communities within large-scale, whole-genome PPINs. Current strategies solve the maximal clique enumeration (MCE) problem, i.e., the enumer...

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Literature Corpus work: 8b9abd8c-0e67-52ab-817d-fcf81c618931
DOI: 10.1101/119099

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