Identifying gene function and module connections by the integration of multi-species expression compendia

Abstract excerpt

The functions of many eukaryotic genes are still poorly understood. We developed and validated a new method, termed GeneBridge, which is based on two linked approaches to impute gene function and bridge genes with biological processes. First, G ene- M odule A ssociation D etermination (G-MAD) allows the annotation of gene function. Second, M odule- M odule A ssociation D etermination (M-MAD) allows predict...

Topics

Open a Topic to create a Post that cites this publication.

• Algorithms
• Computational Biology
• Disease
• Gene Expression Profiling
• Gene Regulatory Networks
• Models, Biological
• Protein Interaction Maps
• Quantitative Trait Loci

Identifiers and source

Literature Corpus work

f0ff051b-6e71-5fae-a3cc-30aaef22cef6

DOI

10.1101/649079