Article

Functional module detection through integration of single-cell RNA sequencing data with protein–protein interaction networks

2019-07-11

Abstract excerpt

Recent advances in single-cell RNA sequencing (scRNA-seq) have allowed researchers to explore transcriptional function at a cellular level. In this study, we present sc PPIN, a method for integrating single-cell RNA sequencing data with protein–protein interaction networks (PPINs) that detects active modules in cells of different transcriptional states. We achieve this by clustering RNA-sequencing data, identifyi...

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Literature Corpus work: 8078ba29-8f13-57c0-97c9-5279295fb9da
DOI: 10.1101/698647

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