Article

Seeing or believing in hyperplexed spatial proteomics via antibodies. New and old biases for an image-based technology

2024-08-06

Abstract excerpt

<h4>ABSTRACT</h4> Hyperplexed in-situ targeted proteomics via antibody immunodetection (i.e. > 15 markers) is changing how we classify cells and tissues. Differently from other high-dimensional single-cell assays (flow cytometry, single cell RNA sequencing), the human eye is a necessary component in multiple procedural steps: image segmentation, signal thresholding, antibody validation and iconographic rendering....

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Literature Corpus work: 8b497700-467c-5a0d-bba7-1ff36a119eb6
DOI: 10.1101/2024.08.02.606335

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