Article

IBEX – A versatile multi-plex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues

2020-11-21

Abstract excerpt

The diverse composition of mammalian tissues poses challenges for understanding the cell-cell interactions required for organ homeostasis and how spatial relationships are perturbed during disease. Existing methods such as single-cell genomics, lacking a spatial context, and traditional immunofluorescence, capturing only 2-6 molecular features, cannot resolve these issues. Imaging technologies have been developed...

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Literature Corpus work: 11fbb843-1277-5028-a5dd-3eac75ade783
DOI: 10.1101/2020.11.20.390690

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