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Article

Spatial proteomic mapping of the human and mouse retina using IBEX

2025-12-22

Abstract excerpt

<h4>Purpose</h4> To generate a comparative spatial proteomic atlas of the human and mouse retina using a refined highly multiplexed immunohistochemistry technique called Iterative Bleaching Extends Multiplexity (IBEX). <h4>Methods</h4> We refined the IBEX workflow by integrating an antibody removal option alongside chemical bleaching. This dual strategy enabled removal of the entire antibody complex allowing for...

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Literature Corpus work
2a4ebca4-0789-522e-a7ae-fee037d4b782
DOI
10.64898/2025.12.19.695231
Open publication

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