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Rapid slide-free histopathology via fluorescent layer-adaptive subcellular imaging: clinical-accessible platform for diverse tissues

2025-04-09

Abstract excerpt

Intraoperative pathology remains constrained by ice crystal artifacts in frozen sections and the high cost of emerging slide-free optical methods. Here, we introduce FLASH-Path, a rapid slide-free technique enabling subcellular-resolution imaging of centimeter-scale tissues in 10 minutes. By replacing mechanical thin sectioning or optical thin-layer excitation with thin-layer (≤10 µm) fluorescent labeling using co...

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Literature Corpus work
11925f1c-3ec7-591d-a9cd-c8470f74ec65
DOI
10.1101/2025.04.07.25325427
Open publication

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Rapid slide-free histopathology via fluorescent layer-adaptive subcellular imaging: clinical-accessible platform for diverse tissuesDOI 10.1101/2025.04.07.25325427
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