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DNA Methylation Silencing of microRNA Gene Methylater in the Precancerous Background Mucosa with and without Gastric Cancer: Analysis of Effects of <em>Helicobacter pylori</em> Eradication and Long-Term Aspirin Use

2019-02-07

Abstract excerpt

The risk of gastric cancer (GC) declines after Helicobacter pylori (H. pylori) eradication and long-term aspirin use. We evaluated the effects of H. pylori eradication (Cohort 1) and aspirin use (Cohort 2) on the methylation of microRNAs (miRNAs) such as miR-34c, miR-124a-3, miR-129-2, and miR-137 in the gastric mucosa with and without GC, i.e., atrophic mucosa (AM) and intestinal metaplasia (IM). DNA was isolated...

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Literature Corpus work
8b489ed5-024c-5e64-9e14-e3d00a4000a8
DOI
10.20944/preprints201902.0070.v1
Open publication

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DNA Methylation Silencing of microRNA Gene Methylater in the Precancerous Background Mucosa with and without Gastric Cancer: Analysis of Effects of <em>Helicobacter pylori</em> Eradication and Long-Term Aspirin UseDOI 10.20944/preprints201902.0070.v1
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