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Long-term effects of H. pylori eradication on epigenetic alterations related to gastric carcinogenesis

19 Sept 2018

Abstract excerpt

The risk of gastric cancer (GC) remains in precancerous conditions, including atrophic mucosa and intestinal mucosa (IM), even after H. pylori treatment. To define the molecular changes following H. pylori eradication, molecular alterations in the gastric mucosa with and without GC were evaluated in a long-term follow-up study. A total of 232 biopsy specimens from 78 consecutive patients, including atrophic...

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PMID: 30254207
DOI: 10.1038/s41598-018-32717-3

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