Article
A non-canonical lysosome biogenesis pathway generates Golgi-associated lysosomes during epidermal differentiation
2018-05-01
Abstract excerpt
Keratinocytes maintain epidermis integrity and function including physical and antimicrobial barrier through cellular differentiation. This process is predicted to be controlled by calcium ion gradient and nutritional stress. Keratinocytes undergo proteome changes during differentiation, which enhances the intracellular organelle digestion to sustain the stress conditions. However, the molecular mechanism between...
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Identifiers and source
- Literature Corpus work
- 8b2f6b9c-8d98-55ea-ba49-d152fd2d983f
- DOI
- 10.1101/312033