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Article

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus.

Nature - 18 Jun 2015

Mochida Keisuke, Oikawa Yu, Kimura Yayoi, Kirisako Hiromi, Hirano Hisashi, Ohsumi Yoshinori, Nakatogawa Hitoshi

Abstract excerpt

Macroautophagy (hereafter referred to as autophagy) degrades various intracellular constituents to regulate a wide range of cellular functions, and is also closely linked to several human diseases. In selective autophagy, receptor proteins recognize degradation targets and direct their sequestration by double-membrane vesicles called autophagosomes, which transport them into lysosomes or vacuoles. Although recent...

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PMID: 26040717
DOI: 10.1038/nature14506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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