Article

Marginated aberrant red blood cells induce pathologic vascular stress fluctuations in a computational model of hematologic disorders

2023-05-18

Abstract excerpt

Red blood cell (RBC) disorders affect billions worldwide. While alterations in the physical properties of aberrant RBCs and associated hemodynamic changes are readily observed, in conditions such as sickle cell disease and iron deficiency, RBC disorders can also be associated with vascular dysfunction. The mechanisms of vasculopathy in those diseases remain unclear and scant research has explored whether biophysic...

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Literature Corpus work: 8b07d218-d83c-5f5c-aac8-26b4eeacb8ed
DOI: 10.1101/2023.05.16.541016

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