Article

Automated detection of the HER2 gene amplification status in Fluorescence <i>in situ</i> hybridization images for the diagnostics of cancer tissues

2018-12-07

Abstract excerpt

The human epidermal growth factor receptor 2 (HER2) gene amplification status is a crucial marker for evaluating clinical therapies of breast or gastric cancer. We propose a deep learning-based pipeline for the detection, localization and classification of interphase nuclei depending on their HER2 gene amplification state in Fluorescence in situ hybridization (FISH) images. Our pipeline combines two RetinaNet-base...

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Identifiers and source

Literature Corpus work: 8aeb5567-0531-5f6c-aa6f-162fbd54a6ab
DOI: 10.1101/490052

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