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Deep learning to automatically evaluate HER2 gene amplification status from fluorescence in situ hybridization images

16 Jun 2023

Abstract excerpt

Human epidermal growth factor receptor 2 (HER2) gene amplification helps identify breast cancer patients who may respond to targeted anti-HER2 therapy. This study aims to develop an automated method for quantifying HER2 fluorescence in situ hybridization (FISH) signals and improve the working efficiency of pathologists. An Aitrox artificial intelligence (AI) model based on deep learning was constructed, and a...

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PMID: 37328516
DOI: 10.1038/s41598-023-36811-z

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