Article

Genomic epidemiological models describe pathogen evolution across fitness valleys

2021-12-17

Abstract excerpt

Genomics is fundamentally changing epidemiological research. However, systematically exploring hypotheses in pathogen evolution requires new modeling tools. Models intertwining pathogen epidemiology and genomic evolution can help understand processes such as the emergence of novel pathogen genotypes with higher transmissibility or resistance to treatment. In this work, we present Opqua, a flexible simulation frame...

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Literature Corpus work: 8adefc53-9657-5a34-96e5-5626e9345f0d
DOI: 10.1101/2021.12.16.473045

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