Article
The impact of bottlenecks on microbial survival, adaptation, and phenotypic switching in host-pathogen interactions.
Evolution; international journal of organic evolution - 1 Dec 2017
Moxon Richard, Kussell Edo
Abstract excerpt
Microbial pathogens and viruses can often maintain sufficient population diversity to evade a wide range of host immune responses. However, when populations experience bottlenecks, as occurs frequently during initiation of new infections, pathogens require specialized mechanisms to regenerate diversity. We address the evolution of such mechanisms, known as stochastic phenotype switches, which are prevalent in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.