Article

Human cell adaptation of the swine acute diarrhea syndrome coronavirus spike protein

2024-08-02

Abstract excerpt

Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a recently identified highly pathogenic swine coronavirus. In vitro, SADS-CoV can infect cell lines from many different species, including humans, highlighting its high zoonotic potential. Coronavirus spike glycoproteins play a critical role in viral entry and are involved in determining viral host range and cellular tropism. Here, we used experimental evolut...

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Literature Corpus work: 8aba9a5e-f833-521d-9e9a-de41aa599099
DOI: 10.1101/2024.07.29.605615

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