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Impact of Mutations Affecting 4’-Fluorouridine Susceptibility on Fitness and Treatment Outcomes for Venezuelan Equine Encephalitis Virus

2025-09-15

Abstract excerpt

Venezuelan equine encephalitis virus (VEEV) is a prototypical encephalitic alphavirus. Members of the Alphavirus genus are found across the globe, transmitted by arthropod vectors, and cause significant disease burdens in humans and animals. There are currently no FDA-approved antivirals against any member of the Alphavirus genus. While a vaccine exists against chikungunya virus (CHIKV), a member of the arthitog...

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Identifiers and source

Literature Corpus work
8a9981dd-fea3-5856-9486-8a113117abd2
DOI
10.1101/2025.09.11.675625
Open publication

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Impact of Mutations Affecting 4’-Fluorouridine Susceptibility on Fitness and Treatment Outcomes for Venezuelan Equine Encephalitis VirusDOI 10.1101/2025.09.11.675625
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