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Article

β-d-N4-Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome.

Journal of virology - 1 Feb 2018

Urakova Nadya, Kuznetsova Valeriya, Crossman David K, Sokratian Arpine, Guthrie David B, Kolykhalov Alexander A, Lockwood Mark A, Natchus Michael G, Crowley Michael R, Painter George R, Frolova Elena I, Frolov Ilya

Abstract excerpt

Venezuelan equine encephalitis virus (VEEV) is a representative member of the New World alphaviruses. It is transmitted by mosquito vectors and causes highly debilitating disease in humans, equids, and other vertebrate hosts. Despite a continuous public health threat, very few compounds with anti-VEEV activity in cell culture and in mouse models have been identified to date, and rapid development of virus...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 29167335
DOI: 10.1128/JVI.01965-17
PMCID: PMC5774879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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β-d-N4-Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome.PMID 29167335Read ↗

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