Article

Functional identification of cis-regulatory long noncoding RNAs at controlled false-discovery rates

2022-09-19

Abstract excerpt

<h4>ABSTRACT</h4> A key attribute of some long noncoding RNAs (lncRNAs) is their ability to regulate expression of neighbouring genes in cis. However, such ‘cis-lncRNAs’ are presently defined using ad hoc criteria that, we show, are prone to false-positive predictions. The resulting lack of cis-lncRNA catalogues hinders our understanding of their extent, characteristics and mechanisms. Here, we introduce TransCis...

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Literature Corpus work: 8a574f8d-d0f7-54ec-a66b-e4a95425aa6c
DOI: 10.1101/2022.09.18.508380

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