Article
Multiple sclerosis.
Immunological reviews - 1 Apr 2005
Hafler David A, Slavik Jacqueline M, Anderson David E, O'Connor Kevin C, De Jager Philip, Baecher-Allan Clare
Abstract excerpt
Multiple sclerosis (MS) is a complex genetic disease associated with inflammation in the central nervous system (CNS) white matter and is thought to be mediated by autoimmune processes. Clonal expansion of B cells, their antibody products, and T cells, hallmarks of inflammation in the CNS, are found in MS. The association of the disease with major histocompatibility complex genes, the inflammatory white matter...
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