Article

Novel LOTUS-domain proteins are organizational hubs that recruit <i>C. elegans</i> Vasa to germ granules

2021-06-17

Abstract excerpt

We describe MIP-1 and MIP-2, novel paralogous C. elegans germ granule components that interact with the intrinsically disordered MEG-3 protein. These proteins promote P granule condensation, form granules independently of MEG-3 in the postembryonic germ line, and balance each other in regulating P granule growth and localization. MIP-1 and MIP-2 each contain two LOTUS domains and intrinsically disordered regions...

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Literature Corpus work: 8a217b17-cb95-5633-88e0-d7c09b1588d5
DOI: 10.1101/2021.06.17.448425

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