Article
Alzheimer’s Disease as a Chronic Maladaptive Polyamine Stress Response
2021-02-17
Abstract excerpt
Polyamines are nitrogen-rich polycationic ubiquitous bioactive molecules with diverse evolutionary-conserved functions. Their activity interferes with numerous genes' expression resulting in cell proliferation and signaling modulation. The intracellular levels of polyamines are precisely controlled by evolutionary-conserved machinery. Their transient synthesis is induced by heat stress, radiation, and other trauma...
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Identifiers and source
- Literature Corpus work
- 8a1e54c8-198e-57c2-abe8-24fa8bc57a32
- DOI
- 10.20944/preprints202102.0362.v1
