Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alzheimer’s disease as a chronic maladaptive polyamine stress response

3 Apr 2021

Abstract excerpt

Polyamines are nitrogen-rich polycationic ubiquitous bioactive molecules with diverse evolutionary-conserved functions. Their activity interferes with numerous genes' expression resulting in cell proliferation and signaling modulation. The intracellular levels of polyamines are precisely controlled by an evolutionary-conserved machinery. Their transient synthesis is induced by heat stress, radiation, and other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Enzymes and Metabolism
Share to Cannabis and Cannabinoid Research
Share to Polyamine Metabolism and Applications

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33811757
DOI: 10.18632/aging.202928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alzheimer’s disease as a chronic maladaptive polyamine stress responsePMID 33811757Read ↗

Alzheimer’s Disease as a Chronic Maladaptive Polyamine Stress ResponseSemantic proximity Read ↗

Protein oxidative modifications in the ageing brain: Consequence for the onset of neurodegenerative diseaseSemantic proximity Read ↗

Carving the senescent phenotype by the chemical reactivity of catecholamines: An integrative review.Semantic proximity Read ↗

Nitric Oxide as a Determinant of Human Longevity and Health SpanSemantic proximity Read ↗

Basic Knowledge of Polyamines That Researchers Must Know before Starting Research, and the Relationship of Polyamines to Aging, Health and DiseaseSemantic proximity Read ↗

Nitric Oxide as a Determinant of Human Longevity and Health SpanSemantic proximity Read ↗

Oxidative Stress and Its Significant Roles in Neurodegenerative Diseases and CancerSemantic proximity Read ↗

Functional Implications of Protein Arginine Methyltransferases (PRMTs) in Neurodegenerative DiseasesSemantic proximity Read ↗

Acute Hypoxia Elevates Arginase 2 and Induces Polyamine Stress Response in Zebrafish via Evolutionary-conserved MechanismSemantic proximity Read ↗

L-norvaline reverses cognitive decline and synaptic loss in a murine model of Alzheimer’s diseaseSemantic proximity Read ↗

Polydopamine nanomedicine-enabled antioxidation against senescenceSemantic proximity Read ↗

Brief Encounters and Lasting Impressions - How Target Half-Life Affects Reactive Metabolite SignalingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.