Article

Multiscale modeling of presynaptic dynamics from molecular to mesoscale

2021-04-18

Abstract excerpt

Chemical synapses exhibit a diverse array of internal mechanisms that affect the dynamics of transmission efficacy. Many of these processes, such as release of neurotransmitter and vesicle recycling, depend strongly on activity-dependent influx and accumulation of Ca 2+ . To model how each of these processes may affect the processing of information in neural circuits, and how their dysfunction may lead to disease...

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Literature Corpus work: 8a0b5b5f-a3da-5342-812d-f9dde97e0a23
DOI: 10.1101/2021.04.16.440229

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