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Integrated transcriptomic analyses identifies host-targeting repurposing drugs for hepatitis C virus infection and related hepatocellular carcinoma

2025-05-23

Abstract excerpt

Hepatitis C virus (HCV) infection is a major risk factor in developing hepatocellular carcinoma (HCC). Drug development for HCV infection and HCC treatment is needed owing to treatment failure due to viral resistance and tumor heterogeneity. We analysed transcriptomic data of human liver tissues from multiple studies to identify differentially expressed genes in four study groups: (HCV+ vs Control); (HCV+HCC+ vs C...

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Literature Corpus work
1bb44077-27ed-5ae3-915e-6b0c8994e452
DOI
10.1101/2025.05.17.654645
Open publication

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Integrated transcriptomic analyses identifies host-targeting repurposing drugs for hepatitis C virus infection and related hepatocellular carcinomaDOI 10.1101/2025.05.17.654645
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