Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2 infection susceptibility influenced by ACE2 genetic polymorphisms: insights from Tehran Cardio-Metabolic Genetic Study.

Scientific reports - 15 Jan 2021

Lanjanian Hossein, Moazzam-Jazi Maryam, Hedayati Mehdi, Akbarzadeh Mahdi, Guity Kamran, Sedaghati-Khayat Bahareh, Azizi Fereidoun, Daneshpour Maryam S

Abstract excerpt

The genetic variations among individuals are one of the notable factors determining disease severity and drug response. Nowadays, COVID-19 pandemic has been adversely affecting many aspects of human life. We used the Tehran Cardio-Metabolic Genetic Study (TCGS) data that is an ongoing genetic study including the whole-genome sequencing of 1200 individuals and chip genotyping of more than 15,000 participants....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme 2
Share to COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to INDEL Mutation

Share to Molecular Docking Simulation

Share to SARS-CoV-2

Share to Serine Endopeptidases

Share to Spike Glycoprotein, Coronavirus

Source

Open in PubMed Open full text

Identifiers

PMID: 33452303
DOI: 10.1038/s41598-020-80325-x
PMCID: PMC7810897

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 infection susceptibility influenced by ACE2 genetic polymorphisms: insights from Tehran Cardio-Metabolic Genetic Study.PMID 33452303Read ↗

ACE2 and TMPRSS2 polymorphisms in various diseases with special reference to its impact on COVID-19 disease.Semantic proximity Read ↗

ACE2 polymorphisms as potential players in COVID-19 outcomeSemantic proximity Read ↗

Susceptibilities of human ACE2 genetic variants in coronavirus infectionSemantic proximity Read ↗

ACE2 polymorphisms as potential players in COVID-19 outcome.Semantic proximity Read ↗

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.Semantic proximity Read ↗

A survey of genetic variants in SARS-CoV-2 interacting domains of ACE2, TMPRSS2 and TLR3/7/8 across populationsSemantic proximity Read ↗

Human ACE2 receptor polymorphisms predict SARS-CoV-2 susceptibilitySemantic proximity Read ↗

Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein.Semantic proximity Read ↗

Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2)Semantic proximity Read ↗

Clinical population genetic analysis of variants in the SARS-CoV-2 receptor ACE2Semantic proximity Read ↗

Variants in ACE2; potential influences on virus infection and COVID-19 severity.Semantic proximity Read ↗

Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.