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Genetic Association of ACE2 rs2285666 Polymorphism With COVID-19 Spatial Distribution in India

25 Sept 2020

Abstract excerpt

Studies on host-pathogen interaction have identified human ACE2 as a host cell receptor responsible for mediating infection by coronavirus (COVID-19). Subsequent studies have shown striking difference of allele frequency among Europeans and Asians for a polymorphism rs2285666, present in ACE2. It has been revealed that the alternate allele (TT-plus strand or AA-minus strand) of rs2285666 elevate the expression...

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PMID: 33101387
DOI: 10.3389/fgene.2020.564741

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