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Article

Engineered reciprocal chromosome translocations drive high threshold, reversible population replacement in Drosophila

2016-11-17

Abstract excerpt

Replacement of wild insect populations with transgene-bearing individuals unable to transmit disease or survive under specific environmental conditions provides self-perpetuating methods of disease prevention and population suppression, respectively. Gene drive mechanisms that require the gene drive element and linked cargo exceed a high threshold frequency to spread are attractive because they offer several point...

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Literature Corpus work
89b4decb-374b-5294-9ddc-c9d38fc80929
DOI
10.1101/088393
Open publication

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Engineered reciprocal chromosome translocations drive high threshold, reversible population replacement in DrosophilaDOI 10.1101/088393
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