Article
Engineered reciprocal chromosome translocations drive high threshold, reversible population replacement in Drosophila
2016-11-17
Abstract excerpt
Replacement of wild insect populations with transgene-bearing individuals unable to transmit disease or survive under specific environmental conditions provides self-perpetuating methods of disease prevention and population suppression, respectively. Gene drive mechanisms that require the gene drive element and linked cargo exceed a high threshold frequency to spread are attractive because they offer several point...
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Identifiers and source
- Literature Corpus work
- 89b4decb-374b-5294-9ddc-c9d38fc80929
- DOI
- 10.1101/088393
