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Integrated single-cell and bulk RNA sequencing analysis identifies the predictive signature for prognosis and neoadjuvant chemotherapy responses in breast cancer

2023-05-05

Abstract excerpt

Neoadjuvant chemotherapy (NAC) is a well-established treatment modality for locally advanced breast cancer (BC). However, it can also result in severe toxicities while controlling tumors. Therefore, reliable predictive biomarkers are urgently needed to objectively and accurately predict NAC response. This study aims to integrate single-cell and bulk RNA-seq data to identify key regulatory factors that contribute t...

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Literature Corpus work
89a138b7-8038-54e6-8ea4-ac5d1b905aa7
DOI
10.21203/rs.3.rs-2805402/v1
Open publication

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Integrated single-cell and bulk RNA sequencing analysis identifies the predictive signature for prognosis and neoadjuvant chemotherapy responses in breast cancerDOI 10.21203/rs.3.rs-2805402/v1
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