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Article

Construction of stemness gene score by bulk and single-cell transcriptome to characterize the prognosis of breast cancer.

Aging - 18 Aug 2023

Lin Jun, Feng Deyi, Liu Jie, Yang Ye, Wei Xujin, Lin Wenqian, Lin Qun

Abstract excerpt

Breast cancer (BC) is a heterogeneous disease characterized by significant differences in prognosis and therapy response. Numerous prognostic tools have been developed for breast cancer. Usually these tools are based on bulk RNA-sequencing (RNA-Seq) and ignore tumor heterogeneity. Consequently, the goal of this study was to construct a single-cell level tool for predicting the prognosis of BC patients. In this...

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PMID: 37602872
DOI: 10.18632/aging.204963
PMCID: PMC10496995

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