Article

Single-cell analyses reveal a simple multi-gene transcriptomic signature with predictive power in prognosis and therapy effectiveness in triple-negative breast cancer

2026-08-13

Abstract excerpt

Triple-negative breast cancer (TNBC) is an aggressive, heterogeneous form of breast cancer with limited specific therapy options, prevalent metastasis and frequent relapse. Re-analysis of single-cell RNA-sequencing data characterizes the diverse cell subtypes within the tumor and microenvironment of TNBC, supporting a luminal progenitor origin for the cancer and providing clues as to the factors involved in progre...

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Literature Corpus work: da396565-3f58-5d3d-9235-0a2de6ecaa2b
DOI: 10.64898/2026.08.12.744411

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