Article

Discovering triple negative breast cancers (TNBC) transcriptomic profiles via massive screening of single cell RNA-sequencing (scRNA-seq) datasets

2022-07-20

Abstract excerpt

<h4>ABSTRACT</h4> Triple negative breast cancers (TNBC) account for 18% of the breast cancer patients in Malaysia and also account for one of the worst prognoses albeit it is the rare cancer types. TNBC is defined as breast cancers that tested negative on all 3 tests of oestrogen/progesterone (ER/PR) receptor and human epidermal growth receptor 2 (HER2). Understanding the TNBC biology is challenging due to the fa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 40dff981-6bf8-5fc5-bbaf-5b81afb9daf6
DOI: 10.1101/2022.07.19.500610

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Discovering triple negative breast cancers (TNBC) transcriptomic profiles via massive screening of single cell RNA-sequencing (scRNA-seq) datasetsDOI 10.1101/2022.07.19.500610Read

Single-Cell RNA-Sequencing: Opening New Horizons for Breast Cancer ResearchSemantic proximity Read

Secondary Transcriptomic Analysis of Triple Negative Breast Cancer Reveals Reliable Universal and Subtype-Specific BiomarkersSemantic proximity Read

Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment StrategiesSemantic proximity Read

Single cell RNA sequencing for breast cancer: present and futureSemantic proximity Read

Malignant cell related gene signature for patients with triple-negative breast cancer based on integrated analysis of single cell and bulk RNA sequencingSemantic proximity Read

A Retrospective View on Triple Negative Breast Cancer Microenvironment: Novel Markers, Interactions, and Mechanisms of Tumor-Associated Components using public Single-cell RNA Seq DatasetsSemantic proximity Read

Identification of New Chemoresistance-Associated Genes in Triple-Negative Breast Cancer by Single-Cell Transcriptomic AnalysisSemantic proximity Read

Triple negative breast cancer (TNBC): Non-genetic tumor heterogeneity and immune microenvironment: Emerging treatment optionsSemantic proximity Read

Single-cell analyses reveal a simple multi-gene transcriptomic signature with predictive power in prognosis and therapy effectiveness in triple-negative breast cancerSemantic proximity Read

Molecular Classification of Breast Cancer Utilizing Long Non-Coding RNA (lncRNA) Transcriptomes Identifies Novel Diagnostic lncRNA Panel for Triple-Negative Breast CancerSemantic proximity Read

Advances in Single-Cell Sequencing Technology and Its Applications in Triple-Negative Breast CancerSemantic proximity Read

An insight into the development of triple-negative breast cancer at transcriptome level based on single-cell sequencing technologySemantic proximity Read