Article

Highly efficient direct conversion of human monocytes into neuronal cells using a small molecule combination

2019-10-13

Abstract excerpt

<h4>Summary</h4> Previous studies reported that human fibroblasts and astrocytes were successfully converted into neuronal cells by small molecules without introducing ectopic transgenes. Induced neuronal cells—reprogrammed directly from dermal fibroblasts or brain astrocytes—were obtained from some donors; however, the clinical applications of this approach would be limited because it requires an invasive biopsy...

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Literature Corpus work: 89663ab9-6701-5bd5-9768-129b9d1f690b
DOI: 10.1101/803254

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