Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypermethylation of CpG Islands in Primary and Metastatic Human Prostate Cancer

15 Mar 2004

Abstract excerpt

Aberrant DNA methylation patterns may be the earliest somatic genome changes in prostate cancer. Using real-time methylation-specific PCR, we assessed the extent of hypermethylation at 16 CpG islands in DNA from seven prostate cancer cell lines (LNCaP, PC-3, DU-145, LAPC-4, CWR22Rv1, VCaP, and C42B), normal prostate epithelial cells, normal prostate stromal cells, 73 primary prostate cancers, 91 metastatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15026333
DOI: 10.1158/0008-5472.can-03-3972

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypermethylation of CpG Islands in Primary and Metastatic Human Prostate CancerPMID 15026333Read ↗

Diagnostic and prognostic information in prostate cancer with the help of a small set of hypermethylated gene loci.Semantic proximity Read ↗

DNA methylation alterations in prostate cancer: from diagnosis to treatmentSemantic proximity Read ↗

Genome-Wide Methylation Analysis of Prostate Tissues Reveals Global Methylation Patterns of Prostate CancerSemantic proximity Read ↗

A DNA hypermethylation profile reveals new potential biomarkers for prostate cancer diagnosis and prognosisSemantic proximity Read ↗

Recent advances in understanding DNA methylation of prostate cancerSemantic proximity Read ↗

Epigenetic Markers for Molecular Detection of Prostate CancerSemantic proximity Read ↗

DNA Methylation-Guided Prediction of Clinical Failure in High-Risk Prostate CancerSemantic proximity Read ↗

Aberrant DNA Methylation and Prostate CancerSemantic proximity Read ↗

Prognostic Value of CpG Island Hypermethylation at PTGS2, RAR-beta, EDNRB, and Other Gene Loci in Patients Undergoing Radical ProstatectomySemantic proximity Read ↗

Multiple Highly Methylated CpG Sites as Potential Epigenetic Markers for the Diagnosis of Prostate CancerSemantic proximity Read ↗

Methylated genes as potential biomarkers in prostate cancerSemantic proximity Read ↗

DNA methylation screening of primary prostate tumors identifies SRD5A2 and CYP11A1 as candidate markers for assessing risk of biochemical recurrenceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.