Article

Construction of an active immune model and electrophysiological study of mice with anti-NMDAR encephalitis

2022-06-27

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>anti-N-methyl-D-aspartate receptor encephalitis is an autoimmune disease, which can show severe neuropsychiatric symptoms, of which seizures are one of the most common symptoms. At present, the mechanism of anti-NMDAR encephalitis is still unclear, and the appropriate animal model is the basis of scientific research.<bold>Methods:</bold> C57BL/6 male mice were a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 88538022-f4ab-52b3-a2a4-21a08868d320
DOI: 10.21203/rs.3.rs-1509233/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Construction of an active immune model and electrophysiological study of mice with anti-NMDAR encephalitisDOI 10.21203/rs.3.rs-1509233/v1Read

NMDA and AMPA Receptor Autoantibodies in Brain Disorders: From Molecular Mechanisms to Clinical FeaturesSemantic proximity Read

NMDA-receptor-Fc-fusion constructs neutralize anti-NMDA receptor antibodiesSemantic proximity Read

Autoantibodies against NMDA receptor 1 modify rather than cause encephalitisSemantic proximity Read

Identification and Characterization of GABAA Receptor Autoantibodies in Autoimmune EncephalitisSemantic proximity Read

Multi-proteomic Analysis Revealed Distinct Protein Profiles in Cerebrospinal Fluid of Patients Between Anti-NMDAR Encephalitis NORSE and Cryptogenic NORSESemantic proximity Read

Autoimmune Encephalitis and Other Neurological Syndromes With Rare Neuronal Surface Antibody in Children after hematopoietic stem cell transplantationSemantic proximity Read

Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity.Semantic proximity Read

Decreased inflammatory cytokine production of antigen-specific CD4<sup>+</sup>T cells in NMDA receptor encephalitisSemantic proximity Read

Anti‐LGI1 encephalitis is associated with unique HLA subtypesSemantic proximity Read

Peptide-Purified Anti-N-Methyl-D-Aspartate (NMDA) Receptor Autoantibodies Have Inhibitory Effect on Long-Term Synaptic PlasticitySemantic proximity Read

Experimental Autoimmune Encephalomyelitis.Semantic proximity Read

Single‐nucleus RNA sequencing unveils critical regulators in various hippocampal neurons for anti‐N‐methyl‐D‐aspartate receptor encephalitisSemantic proximity Read