Article

Germ-free piglets display variable neuroinflammatory-like perturbations in prefrontal cortical microglia

2026-03-24

Abstract excerpt

Communication between gut microbiota and immune cells within the brain is essential for neurotypical development. Specifically, microglia are known to play a key role in regulating and supporting neural progenitor stem cell production during brain development, and are sensitive to changes in the maternal gut microbial composition during perinatal development. Here, we employed a germ-free (GF) porcine paradigm to...

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Literature Corpus work: 884456e8-681f-5bc5-9f2f-12bb6ce888e3
DOI: 10.64898/2026.03.22.713463

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