Article

Clusterin can mediate apoptosis-induced molecular mechanisms in immune thrombocytopenia

2023-09-27

Abstract excerpt

Abnormalities in the apoptosis pathway are possible risk factors for various autoimmune diseases including immune thrombocytopenia (ITP). ITP is an autoimmune bleeding disorder characterized by a low platelet count and mostly mild but in rare occasions life threatening bleeding symptoms. Platelets and megakaryocytes (MKs) may be seen as the major targets of the pathogenic immune responses in ITP. A mechanistic und...

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Literature Corpus work: 8843819e-d6e0-5df5-8884-b3b32e799363
DOI: 10.1101/2023.09.26.559483

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