Article

DeSide: A unified deep learning approach for cellular decomposition of bulk tumors based on limited scRNA-seq data

2023-05-14

Abstract excerpt

Cellular decomposition employing bulk RNA-sequencing (RNA-seq) has been consistently under investigation due to its high fidelity, ease of use, and cost-effectiveness compared to single cell RNA-sequencing (scRNA-seq). However, the intricate nature of the tumor microenvironment, and the significant heterogeneity among patients and cells have made it challenging to precisely evaluate the cellular composition of sol...

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Literature Corpus work: 87ab1b79-19be-5165-ba1a-3145b6065e56
DOI: 10.1101/2023.05.11.540466

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