Article
Novel approaches using human induced pluripotent stem cells and microRNAs in the development of relevant human hepatocyte models for drug-induced liver injury
2014-01-01
Abstract excerpt
Drug-induced liver injury (DILI) remains a prominent cause of patient morbidity and mortality, partly due to the lack of relevant in vitro hepatic models for accurate screening for drug-induced hepatotoxicity at the early stages of drug development, and also the lack of sophisticated in vitro model systems to mechanistically understand the pathways that are perturbed following drug exposure. This thesis describes...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 87761ba8-af5e-550f-af61-3c62825bf737
- DOI
- 10.17638/02010059