Article
Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malaria
2021-05-12
Abstract excerpt
Recent initiatives to improve translation of findings from animal models to human disease have focussed on reproducibility but quantifying the relevance of animal models remains a challenge. Here we use comparative transcriptomics of blood to evaluate the systemic host response and its concordance between humans with different clinical manifestations of malaria and five commonly used mouse models. Plasmodium yoel...
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Identifiers and source
- Literature Corpus work
- 87647ead-da9f-5e3a-be93-24e5e62dffff
- DOI
- 10.1101/2021.05.11.443626