Article

Deep learning predicts HRD and platinum response from histology slides in breast and ovarian cancer

2023-02-26

Abstract excerpt

<h4>ABSTRACT</h4> Breast and ovarian cancers harboring homologous recombination deficiencies (HRD) can benefit from platinum-based chemotherapies and PARP inhibitors. Standard diagnostic tests for detecting HRD utilize molecular profiling, which is not universally available especially for medically underserved populations. Here, we trained a deep learning approach for predicting genomically derived HRD scores fro...

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Literature Corpus work: 873ac60a-c54c-5a4a-8972-8386f1461a78
DOI: 10.1101/2023.02.23.23285869

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