Article

Common anesthetic used in preclinical PET imaging inhibits metabolism of the PET tracer [ <sup>18</sup> F]3F4AP

2023-12-14

Abstract excerpt

<h4>ABSTRACT</h4> PET imaging studies in laboratory animals are almost always performed under isoflurane anesthesia to ensure that the subject stays still during the image acquisition. Isoflurane is effective, safe, and easy to use, and it is generally assumed to not have an impact on the imaging results. Motivated by marked differences observed in [ 18 F]3F4AP brain uptake and metabolism between human and nonhu...

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Literature Corpus work: 87135f8b-808a-5e34-8b2a-81e5e334a3b3
DOI: 10.1101/2023.12.14.571690

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