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Article

Concordance of Genomic Alterations in Ovarian Cancer Tissues and Circulating-Tumor DNA: A Pilot Study.

International journal of molecular sciences - 28 Jan 2026

Kang Bowon, Kim Seongmin, Lee Sanghoon, Song Jae Yun

Abstract excerpt

High-grade serous ovarian carcinoma (HGSOC) is characterized by profound genomic instability and spatial heterogeneity. Liquid biopsy, utilizing circulating tumor DNA (ctDNA), offers a non-invasive approach to capture the comprehensive mutational landscape of the disease. This pilot study evaluated the concordance of genomic alterations between cell-free DNA (cfDNA) and matched tumor tissue in patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41683736
DOI: 10.3390/ijms27031305
PMCID: PMC12897642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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