Article
Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA: a structural scaffold for nuclear, cytoplasmic and viral proteins.
Nucleic acids research - 20 Jun 2017
Sztuba-Solinska Joanna, Rausch Jason W, Smith Rodman, Miller Jennifer T, Whitby Denise, Le Grice Stuart F J
Abstract excerpt
Kaposi's sarcoma-associated herpes virus (KSHV) polyadenylated nuclear (PAN) RNA facilitates lytic infection, modulating the cellular immune response by interacting with viral and cellular proteins and DNA. Although a number nucleoprotein interactions involving PAN have been implicated, our understanding of binding partners and PAN RNA binding motifs remains incomplete. Herein, we used SHAPE-mutational profiling...
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