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Negative selection on a <i>SOD1</i> mutation limits canine degenerative myelopathy while avoiding inbreeding

2023-07-26

Abstract excerpt

Several hundred disease-causing mutations are currently known in domestic dogs. Breeding management is therefore required to minimize their spread. Recently, genetic methods such as direct-to-consumer testing have gained popularity; however, their effects on dog populations are unclear. Here, we aimed to evaluate the influence of genetic testing on the frequency of mutations responsible for canine degenerative mye...

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Literature Corpus work
86b52507-b6fb-59b7-ae87-682d6df263a6
DOI
10.1101/2023.07.25.550492
Open publication

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Negative selection on a <i>SOD1</i> mutation limits canine degenerative myelopathy while avoiding inbreedingDOI 10.1101/2023.07.25.550492
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